Holland's career began at the age of nine when he enrolled in a dancing class. A choreographer noticed him and arranged for him to audition for a role in Billy Elliot the Musical at London's Victoria Palace Theatre. After two years of training, he secured a supporting part in 2008. Later that year, he was upgraded to the title role, which he played until 2010. Holland made his film debut in the disaster drama The Impossible (2012) as a teenage tourist trapped in a tsunami; he received critical acclaim and a nomination for the Goya Award for Best New Actor. Holland then decided to pursue acting as a full-time career, appearing in How I Live Now (2013) and playing historical figures in the film In the Heart of the Sea (2015) and the TV miniseries Wolf Hall (2015).
Holland achieved international recognition playing Peter Parker/Spider-Man in six Marvel Cinematic Universe (MCU) superhero films, beginning with Captain America: Civil War (2016). The following year, Holland received the BAFTA Rising Star Award and became the youngest actor to play a title role in an MCU film in Spider-Man: Homecoming. Its sequels, Far From Home (2019) and No Way Home (2021), each grossed more than $1 billion worldwide; the latter became the highest-grossing film of the year. Holland played another action film role in Uncharted (2022), and also expanded to play against-type roles in the crime dramas The Devil All the Time (2020) and Cherry (2021). Holland has directed the short film Tweet (2015) and voiced roles in animated features, including Spies in Disguise (2019) and Onward (2020).
Holland executive produced and starred in the Apple TV+ miniseries The Crowded Room (2023), inspired by the 1981 non-fiction novel The Minds of Billy Milligan, in which he played a character based on Billy Milligan. He made a return to the stage as Romeo in Jamie Lloyd's West End revival of Romeo and Juliet, which ran for twelve weeks from May 2024.
In 2024, Holland created his own production company, named Billy17, and landed a deal with Sony Pictures. Among his upcoming films, he will star in Christopher Nolan's film The Odyssey, an adaptation of the epic poem the Odyssey, written by Homer.
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