Born and raised in Spanish Harlem, Karmine has been singing since the age of 13, which later led her to study voice in high school. At 17, she joned a 3-girl vocal group which took her on the road, where she performed all over the states.
She joined other bands while attending college, where she took courses in acting and dance.
Karmine went on to do children shows and industrials, as well as landing a few spots in some independent shorts.
Karmine's singing career would pull her again into a new 3-girl vocal group, this time landing her a recording deal with A&M records. The band "3RD Party" recorded an album, filmed their video and traveled nationwide. The band also performed on TV shows such as Regis and Kathie Lee, Rupaul, Jenny Jones and The Today Show.
Karmine was then called to be in the Broadway show RENT. After touring with the National Benny Company of RENT, she was hired for the Broadway company as an understudy. In January of 2002, she took over the leading role of Mimi.
Karmine has since been focusing on developing & promoting her debut solo album.