VIDEO: Watch the Official Trailer for THE SISTERS BROTHERS Starring Joaquin Phoenix, Jake Gyllenhaal, & John C. Reilly

Based on Patrick Dewitt's acclaimed novel of the same name, follows two brothers - Eli and Charlie Sisters - who are hired to kill a prospector who has stolen from their boss. The story, a genre-hybrid with comedic elements, takes place in Oregon in 1851. The film is Jacques Audiard's follow-up to his Palme D'Or Winning DHEEPAN, which premiered at the 2015 Cannes Film Festival.

Directed by Jacques Audiard, the film stars Joaquin Phoenix, John C. Reilly, Jake Gyllenhaal, and Riz Ahmed. Watch the trailer below!

2026 Theater Fans' Choice Awards - Live Stats

Best Original Score - Top 3

1. The Rescues , The Rescues - The Lost Boys

40.9% of votes

2. Jim Barne, Kit Buchan - Two Strangers (Carry a Cake Across New York)

29.3% of votes

3. Cinco Paul - Schmigadoon!

22.6% of votes

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