Rx Machina unpacks big pharmas impact on everyday American culture through the eyes of five women on the frontlines of the opioid epidemic. An ambitious drug sales reps relentless pursuit of a principled pain management doctor leads to an intoxicating, forbidden connection that comes with a cost. Ethical boundaries are blurred in a love triangle fueled by money, sex, and power. In a world where patients are consumers and pain is profitable, Rx Machina asks the important question Who gets better, and who gets left behind?