Sometimes you get thrown a curveball. Open Fist Theatre Company presents the world premiere of a darkly funny comedy about family, baseball, genetics and the unexpected vagaries of life. Twenty years after the Red Sox lost their chance at the pennant when a Yankees fan bounded onto the field in the ninth inning to void what would have been the game-winning out, Sisters Kelly Moran and Maureen Dugan still live on the Irish Riviera south of Boston, where they were known as hard girls back in high school. Oct. 1 Nov. 5; Open Fist Theatre Company @ Atwater Village Theatre, 3269 Casitas Ave., Los Angeles, CA 90039; $15-$30; www.openfist.org