VIDEO: First Look - Melissa McCarthy, Bill Murray Star in New Comedy ST. VINCENT

Bill Murray, Melissa McCarthy, Chris O'Dowd, and Naomi Watts star in th enew comedy ST. VINCENT, hitting theaters on October 24th.

Below, get a first look look at the trailer for The Comedy directed by Ted Melfi.

When Maggie (McCarthy), a single mother, moves into a new home in Brooklyn with her 12-year old son, Oliver (Lieberher), she is forced to leave Oliver in the care of their new neighbor, Vincent (Murray), "a retired curmudgeon with a penchant for alcohol and gambling".