Khloe Kardashian & More to Serve as CHELSEA LATELY Celebrity Guest Hosts Next Week

Starting April 21, Chelsea Handler welcomes some famous faces to take over her show when Khloé Kardashian, T.J. Miller, Loni Love and Mary McCormack make "Chelsea Lately" their own.

From running her raucous roundtable to keeping a watchful eye over her mischievous nugget Chuy, these celebrity squatters are moving in on Chelsea's turf and the lives of her staff will never be the same. Kicking things off on April 21 is returning fan favorite Khloé Kardashian, followed by the hilarious T.J. Miller on April 22, with Loni Love reigning supreme on April 23, and actress Mary McCormack rounding out guest host week on April 24.

· Monday, April 21: The always outspoken Khloé Kardashian returns to take over "Chelsea Lately" when she hosts with special guest Bob Saget discussing his new book, "Dirty Daddy."

· Tuesday, April 22: TV star and funnyman T.J. Miller brings his no holds barred sense of humor as host with guest Wiz Khalifa talking about his new single "We Dem Boyz."

· Wednesday, April 23: Loni Love gets Revenge on her frenemy Chelsea and commands the stage with guest Mekhi Phifer discussing his new film, "The Suspect."

· Thursday, April 24: The hilarious Mary McCormack returns with her unique brand of funny with special guest and star of The Vampire Diaries, Ian Somerhalder.

Chelsea's celebrity friends take over April 21, 22, 23 and 24 at 11:00pm ET/PT only on E!