Cool idea, but to play devil's advocate....isn't there A LOT of story to fit into one musical? It would be a shame to see this turn into a COLOR PURPLE thing of "it almost worked, but they tried to pack too much in". The great thing about Maupin's books were how light and frothy they were...blowing it up could, well, blow it up.
"Impossible is just a big word thrown around by small men who find it easier to live in the world they've been given than to explore the power they have to change it. Impossible is not a fact. It's an opinion. Impossible is not a declaration. It's a dare. Impossible is potential. Impossible is temporary. Impossible is nothing.”
~ Muhammad Ali
This is actually not a bad fit. Scissor Sisters have kind of a disco retro sound anyway. I think you could easily pick and choose the story lines you wanted to use. Probably the one with Mrs. Madrigal and the rich guy, Michael and John, and Maryanne would have to come in somewhere... I guess...