Melissa McCarthy Videos

Comic actress Melissa McCarthy plays a wealthy woman trying to get back on her feet after a prison stretch for insider trading in the new film “The Boss.”

Who you gonna call? It's Girls vs. Ghouls in the much-anticipated GHOSTBUSTERS reboot, starring Melissa McCarthy, Kristen Wiig, Kate McKinnon and Leslie Jones.

Courteney Cox, David Schwimmer, Jennifer Aniston, Lisa Kudrow and Matt LeBlanc explain how Director Jim Burrows brought them together on 'Friends.'

In the video below, Columbia Pictures announces that the first official trailer for Paul Feig's GHOSTBUSTERS will debut online on March 3rd!

Melissa McCarthy hosts alongside musical guest Kanye West. Sketches include Hillary Clinton Cold Open, Melissa McCarthy Five-Timers Monologue, Beyoncé Trailer, Kyle vs. Kanye and Whiskers R We with Melissa McCarthy. Check out the full episode below!

Melissa McCarthy returns to SATURDAY NIGHT LIVE for her fourth time as host tonight, with special musical guest Kanye West. Below, check out the latest promo featuring McCarthy, West, and cast member Colin Jost!

SOMETHING ROTTEN's Brian d'Arcy James stopped by last night's LATE NIGHT, and recalled meeting Hillary Clinton backstage at the off-Broadway production of HAMILTON riding on ah ight of caffeine and awards ceremony addiction and Broadwa

On last night's PEOPLE'S CHOICE AWARDS, Melissa McCarthy presented Ellen DeGeneres with the award for Favorite Humanitarian, presented by Walgreens.

Starz today announced the highly anticipated return of original series “Power” tonight, June 6th at 9pm ET/PT. The second season of “Power” features ten hour-long episodes, a bump from the first season's order of eight episodes.

On last night's THE DAILY SHOW, actress Melissa McCarthy discussed her Jon Stewart kimono as well as working with Jason Statham and learning gun safety for her movie 'Spy.'

On last night's LATE NIGHT, guest Melissa McCarthy chatted about working with a former CIA agent on her new comedy 'Spy.' Watch clips from the appearance below!

The actress talks about reuniting with Bridesmaids director Paul Feig and actress Melissa McCarthy in her latest film.

McCarthy talks to Jimmy about being honored with a star on the Hollywood Walk of Fame and about her film Spy and the crazy stunts she didn't realize she'd have to perform.

Funny woman Melissa McCarthy plays a CIA analyst with a secret crush on agent Jude Law in the new film SPY.

MTV has debuted a new clip from 20th Century Fox's secret agent comedy SPY, featuring Melissa McCarthy and Rose Byrne. The film hits theaters on June 5, 2015.

Below, watch the brand new trailer for SPY, starring Jason Statham and Melissa McCarthy. The film hits theaters on June 5, 2015.

20th Century Fox has shared the first trailer for the new Melissa McCarthy in the secret agent spoof SPY. The film hits theaters on May 22nd. Get a first look below, courtesy of Yahoo!

The queen of comedy, Melissa McCarthy stopped by NBC's TODAY to talk about starring opposite Bill Murray in her new film, 'St. Vincent.' The actress also addressed recent rumors that she will be appearing in the recently announced sequel to 'Ghostbusters.'

To commenorate the final episode of Chelsea Handler's nightly E! Talk Show CHELSEA LATELY, Handler invited a number of famous faces to say goodbye in song. Joining Handler were stars Gwen Stefani, Dave Grohl, Fergie, Avril Lavigne, Melissa McCarthy, Selena Gomez, Sandra Bullock, and more.

Oscar winner Susan Sarandon stopped by this morning's GMA to talk about 'cankles' and dishes about her new role as Melissa McCarthy's grandma in the comedy TAMMY, now in theaters.