In the episode “Medusa” — (8:00-9:00 p.m. ET) Eliza (guest star Helen Slater) comes to town to celebrate Thanksgiving with her daughters. Alex (Chyler Leigh) decides it’s time to come out to her mother; Kara (Melisa Benoist) is shocked when Eliza suggests Mon-El (Chris Wood) has feelings for her, and Winn (Jeremy Jordan) and James (Mehcad Brooks) consider telling Kara the truth about the Guardian. Meanwhile, CADMUS unleashes a virus that instantly kills any alien in the vicinity so Kara enlists an unexpected ally – Lena Luthor (Katie McGrath). The epic superhero crossover kicks off tonight when Barry Allen (guest star Grant Gustin) and Cisco Ramon (guest star Carlos Valdes) seek Kara’s help with an alien invasion on their Earth. Stefan Pleszczynski directed the episode written by Jessica Queller & Derek Simon (#208). Original airdate 11/28/2016.
Melissa Benoist leads the cast of Supergirl as the title character alongside Mehcad Brooks as James Olsen, Laura Benanti as Alura Zor-El, Calista Flockhart as Cat Grant, Chyler Leigh as Alexandra “Alex” Danvers, Jeremy Jordan as Winslow “Winn” Schott, Jenna Dewan Tatum as Lucy Lane (sister of Lois), David Harewood as Hank Henshaw, Peter Facinelli as Maxwell Lord, with Dean Cain and Helen Slater. ?
SUPERGIRL is based on the DC character Kara Zor-El, Superman's cousin, who after 12 years of keeping her powers a secret on Earth, decides to finally embrace her superhuman abilities and be the hero she was always meant to be. Kara lives in National City assisting media mogul Cat Grant. However, Kara's days of keeping her talents a secret are over when Hank Henshaw, head of a super-secret agency, enlists her to help protect the citizens of National City from sinister threats.
