Debra Messing Among Upcoming Guests on LATE SHOW WITH DAVID LETTERMAN, 3/21

Debra Messing will be among the upcoming guests on CBS's LATE SHOW with DAVID LETTERMAN. The show airs Monday - Fridays at 11:35 PM-12:37 AM on the CBS network. 

Other guests for the weeks of 3/16-3/27 include: 

(*Denotes changes and/or additions to previous schedule. (n) Denotes new broadcast)

Friday, March 16 Actress Reese Witherspoon; actor Michael Weatherly from the CBS drama series “NCIS”; musical guest Kasabian; a Top Ten List presented by 10 Sports Illustrated Swimsuit models

Monday, March 19 First Lady Michelle Obama; musical guest Esperanza Spalding

*Tuesday, March 20 Actress Jennifer Lawrence; journalist/author Gail Collins; musical guests The Shins (n)

Wednesday, March 21 Actress Debra Messing; actor Josh Hutcherson; musical guests Oberhofer (n)

*Thursday, March 22 Actor Paul Rudd; comedian John Witherspoon; musical guests Heartless Bastards

*Friday, March 23 New York Giants quarterback Eli Manning; actress Sarah Michelle Gellar; musical guests Die Antwoord

*Monday, March 26 Journalist Rachel Maddow; actor Timothy Olyphant; musical guests Train (n)

*Tuesday, March 27 Musician Lionel Richie; musical guests Lionel Richie with Jason Aldean (n)

The critically acclaimed, multi-award-winning LATE SHOW WITH DAVID LETTERMAN has remained one of the funniest and most creative shows on television. The program, which is often imitated but never matched, is unlike any other talk show. With its commitment to showcasing the most sought-after stars in entertainment, music, sports and politics, as well as its around-the-town remotes and visits to local establishments, its surprise guest appearances, inventive comedy segments and signature Top Ten List, the LATE SHOW delivers an unpredictable hour of innovative viewing each night.

The LATE SHOW has received numerous honors, including 71 Emmy nominations and nine Emmy Awards, including six for Outstanding Variety, Music or Comedy Program in 1994, 1998, 1999, 2000, 2001 and 2002. The show was named Program of the Year at the 1994 Television Critics Awards, and in 1995, 2001 and 2011, Letterman was nominated for a Career Achievement Award by the TCA. Letterman was awarded the prestigious Johnny Carson Award for Comedic Excellence at Comedy Central’s first annual “The Comedy Awards” in March 2011. He has won two American Comedy Awards as Funniest Male Performer in a Television Series and a Foundation Award from the International Radio and Television Society for his "extraordinary domi­nation in late-night television." Letterman was also honored as "Favorite Late Night Talk Show Host" at the 31st Annual People's Choice Awards in 2005.